Information on these possible side effects have been included in the Patient Information Leaflet and product information since 2012 (gambling) and 2018 (other impulse control disorders). In March 2023, the MHRA asked gambling clinics to report any suspected cases which may account for some of the rise.

Thirty-two of these reports were received between 1 January and 31 August this year. In the last 14 years, the MHRA’s Yellow Card scheme received 69 reports of gambling or gambling disorder where aripiprazole was suspected to be the cause. Stopping aripiprazole without medical advice can be harmful. Patients should continue taking aripiprazole as advised.

Patients are advised to tell their doctor if they or their family and friends notice they are having unusual urges or cravings that they cannot resist, including behaviours such as addictive gambling, excessive eating or spending, or an abnormally high sex drive. Aripiprazole is an important medicine for the treatment of schizophrenia and bipolar disorder.